Volume 40, Issue 12

Magnetic resonance imaging (MRI) can provide multiple contrast-weighted images using different pulse sequences and protocols. However, a long acquisition time of the images is a major challenge. To address this limitation, a new pulse sequence referred to as quad-contrast imaging is presented. The quad-contrast sequence enables the simultaneous acquisition of four contrast-weighted images (proton ...

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In this paper, we discuss the design study for a brain SPECT imaging system, referred to as the HelmetSPECT system, based on a spherical synthetic compound-eye (SCE) gamma camera design. The design utilizes a large number ( $\sim 500$ ) of semiconductor detector modules, each coupled to an aperture with a very narrow opening for high-resolution SPECT imaging applications. In this study, we demonst...

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A novel divergence-free constrained phase unwrapping method was proposed and evaluated for 4D flow MRI. The unwrapped phase field was obtained by integrating the phase variations estimated from the wrapped phase data using weighted least-squares. The divergence-free constraint for incompressible blood flow was incorporated to regulate and denoise the resulting phase field. The proposed method was ...

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Perfusion imaging is of great clinical importance and is used to assess a wide range of diseases including strokes and brain tumors. Commonly used approaches for the quantitative analysis of perfusion images are based on measuring the effect of a contrast agent moving through blood vessels and into tissue. Contrast-agent free approaches, for example, based on intravoxel incoherent motion and arter...

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Optoacoustic signals are typically reconstructed into images using inversion algorithms applied in the time-domain. However, time-domain reconstructions can be computationally intensive and therefore slow when large amounts of raw data are collected from an optoacoustic scan. Here we considered a fast weighted ${\omega }-{k}$ (FWOK) algorithm operating in the frequency domain to accelerate the i...

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In myocardial perfusion imaging with dynamic positron emission tomography (PET), direct parametric reconstruction from the projection data allows accurate modeling of the Poisson noise in the projection domain to provide more reliable estimate of the parametric images. In this study, we propose to incorporate a superior denoiser to efficiently suppress the unfavorable noise propagation during the ...

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In MR Fingerprinting (MRF), balanced Steady-State Free Precession (bSSFP) has advantages over unbalanced SSFP because it retains the spin history achieving a higher signal-to-noise ratio (SNR) and scan efficiency. However, bSSFP-MRF is not frequently used because it is sensitive to off-resonance, producing artifacts and blurring, and affecting the parametric map quality. Here we propose a novel Sp...

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Correction of ${B}_{1}$ field non-uniformity is critical for many quantitative MRI methods including variable flip angle (VFA) ${T}_{1}$ mapping and single-point macromolecular proton fraction (MPF) mapping. The latter method showed promising results as a fast and robust quantitative myelin imaging approach and involves VFA-based ${R}_{1}=1/{T}_{1}$ map reconstruction as an intermediate proc...

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Biophysical models are a promising means for interpreting diffusion weighted magnetic resonance imaging (DW-MRI) data, as they can provide estimates of physiologically relevant parameters of microstructure including cell size, volume fraction, or dispersion. However, their application in cardiac microstructure mapping (CMM) has been limited. This study proposes seven new two-compartment models wit...

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In the above article [1], Figs. 5 and 6 were published incorrectly. The correct figures are given below:

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In the above article [1], one error, (1), was found which has an impact on the results and interpretation of the image quality that was described in four sentences, (2)–(5). This correction does not mitigate the overall conclusion of this work, but does positively support improvements of the proposed method (multi-perspective ultrafast imaging) in comparison with the standard method (focused line-...

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Presents the table of contents for this issue of the publication.

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